Effect of equiosmolar solutions of hypertonic sodium lactate versus mannitol in craniectomy patients with moderate traumatic brain injury
ثبت نشده
چکیده
Latar belakang: Kraniektomi memerlukan relaksasi otak dan pencegahan edema cerebri. Hal tersebut dicapai dengan osmoterapi yang bertujuan menarik cairan dari parenkim otak. Selama ini digunakan manitol 20% namun dapat mengganggu hemodinamik karena merangsang produksi urin. Sodium laktat hipertonik 0,5M (SLH) merupakan zat alternatif untuk menurunkan edema cerebri dan memberi relaksasi. Penelitian ini bertujuan melihat pengaruh SLH terhadap relaksasi otak, kadar glukosa darah, dan hemodinamik pada pasien kraniektomi akibat cedera otak sedang.
منابع مشابه
Salt or sugar for your injured brain? A meta-analysis of randomised controlled trials of mannitol versus hypertonic sodium solutions to manage raised intracranial pressure in traumatic brain injury.
BACKGROUND Rising intracranial pressure (ICP) is a poor prognostic indicator in traumatic brain injury (TBI). Both mannitol and hypertonic sodium solutions are used to treat raised ICP in patients with TBI. OBJECTIVE This meta-analysis compares the use of mannitol versus hypertonic sodium solutions for ICP control in patients with TBI. DATA SOURCES AND STUDY ELIGIBILITY Randomised clinical ...
متن کاملEffect of equiosmolar solutions of mannitol versus hypertonic saline on intraoperative brain relaxation and electrolyte balance.
BACKGROUND The purpose of the study was to compare the effect of equiosmolar solutions of mannitol and hypertonic saline (HS) on brain relaxation and electrolyte balance. METHODS After institutional review board approval and informed consent, patients with American Society of Anesthesiologists physical status II-IV, scheduled to undergo craniotomy for various brain pathologies, were enrolled ...
متن کاملHypertonic saline for craniotomy?
IN this issue of ANESTHESIOLOGY, Rozet et al. present the findings of a comprehensive study comparing two hyperosmolar agents, hypertonic saline (HS) and mannitol, for brain relaxation during craniotomy. This work calls into question whether sufficient information is now available to advocate substitution of mannitol with HS to promote brain relaxation during routine craniotomy. It was discover...
متن کاملContemporary management of traumatic intracranial hypertension: is there a role for therapeutic hypothermia?
OBJECTIVE Intracranial hypertension (ICH) remains the single most difficult therapeutic challenge for the acute management of severe traumatic brain injury (TBI). We reviewed the published trials of therapeutic moderate hypothermia to determine its effect on ICH and compared its efficacy to other commonly used therapies for ICH. METHODS A PubMed database search was done using various combinat...
متن کاملClinical Studies Effects of 23.4% Sodium Chloride Solution in Reducing Intracranial Pressure in Patients with Traumatic Brain Injury: a Preliminary Study
Accepted, April 28, 2005. OBJECTIVE: Mannitol is the standard of care for patients with increased intracranial pressure (ICP), but multiple administrations of mannitol risk renal toxicity and fluid accumulation in the brain parenchyma with consequent worsening of cerebral edema. This preliminary study assessed the safety and efficacy of small-volume injections of 23.4% sodium chloride solution ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014